a patient with primary biliary cirrhosis accompanied by wilson’s disease

A Patient With Primary Biliary Cirrhosis Accompanied by Wilson’s Disease

INTRODUCTION Both primary biliary cirrhosis (PBC) and Wilson's disease (WD) can cause copper retention in the liver, which is an important factor for liver cellular damage. Copper chelation may preserve liver cell function. It is challenging to distinguish WD from copper accumulation in patients with PBC. There have been few case reports of PBC co-occurrence with WD. CASE PRESENTATION Here we...

Liver damage in primary biliary cirrhosis and accompanied by primary Sjögren's syndrome: a retrospective pilot study

INTRODUCTION Primary biliary cirrhosis (PBC) and primary Sjögren's syndrome (pSS) have been referred to as "generalized autoimmune epithelitis". Indeed, the pathogenic mechanisms, clinical features, and optimal therapeutic approaches for them are not yet fully defined. MATERIAL AND METHODS A retrospective analysis was carried out on clinical data obtained from 302 inpatients newly diagnosed w...

Lymphocytic bronchitis/bronchiolitis in a patient with primary biliary cirrhosis.

A 39 year old woman with severe primary biliary cirrhosis progressively developed exercise dyspnoea due to airflow obstruction. Sjögren's syndrome was not present. Bronchial and pulmonary biopsies demonstrated constrictive lymphocytic bronchitis/bronchiolitis, possibly a component of a generalized autoimmune process in this patient.

A patient with primary biliary cirrhosis and elevated LDL cholesterol.

A 47-year-old woman was referred to us for follow-up of primary biliary cirrhosis (PBC). She reported nausea, malaise, weight loss, and new-onset jaundice. The patient had recently had an episode of melena with anemia requiring blood transfusions, but upper endoscopy and colonoscopy did not reveal a bleeding source. She reported a smoking history of 30 years and was currently smoking. The patie...

Primary biliary cirrhosis in a patient with interstitial lung fibrosis.

Primary biliary cirrhosis associated with Graves' disease in a male patient.

Primary biliary cirrhosis (PBC), which predominantly affects women, has been associated with various autoimmune diseases. Although hypothyroidism accompanying PBC is well documented, the concomitance of PBC and hyperthyroidism is rare. Herein, we report the case of a 62-year-old man who was diagnosed with PBC several years after the development of Graves' disease. This is the first case of a ma...